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Bruce E Mickey Selected Research

alpha-hydroxyglutarate

10/2021Spectral fitting strategy to overcome the overlap between 2-hydroxyglutarate and lipid resonances at 2.25 ppm.
1/2020In vivo MRS measurement of 2-hydroxyglutarate in patient-derived IDH-mutant xenograft mouse models versus glioma patients.
1/2020Glycine by MR spectroscopy is an imaging biomarker of glioma aggressiveness.
1/20193D high-resolution imaging of 2-hydroxyglutarate in glioma patients using DRAG-EPSI at 3T in vivo.
1/2018Echo-planar spectroscopic imaging with dual-readout alternated gradients (DRAG-EPSI) at 7 T: Application for 2-hydroxyglutarate imaging in glioma patients.
1/2017In vivo detection of 2-hydroxyglutarate in brain tumors by optimized point-resolved spectroscopy (PRESS) at 7T.
1/2017Detection of 2-hydroxyglutarate in brain tumors by triple-refocusing MR spectroscopy at 3T in vivo.
11/2016Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma.
1/20122-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.

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Bruce E Mickey Research Topics

Disease

18Neoplasms (Cancer)
10/2021 - 04/2009
11Glioma (Gliomas)
11/2021 - 11/2009
8Brain Neoplasms (Brain Tumor)
10/2021 - 09/2011
8Glioblastoma (Glioblastoma Multiforme)
01/2021 - 04/2009
2Hemangiopericytoma
08/2017 - 04/2013
1Lymphadenopathy
03/2020
1Ependymoma
03/2020
1Nervous System Diseases (Neurological Disorders)
09/2017
1Neoplasm Metastasis (Metastasis)
08/2017
1Oligodendroglioma
11/2016
1Astrocytoma (Pilocytic Astrocytoma)
11/2016
1Hypophosphatemia
04/2013
1Oncogenic osteomalacia
04/2013
1Osteomalacia
04/2013
1Acoustic Neuroma (Acoustic Neurinoma)
02/2012
1Inflammation (Inflammations)
08/2008

Drug/Important Bio-Agent (IBA)

9alpha-hydroxyglutarateIBA
10/2021 - 01/2012
5Glucose (Dextrose)FDA LinkGeneric
11/2017 - 11/2009
4Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2021 - 11/2016
3Lactic Acid (Lactate)FDA LinkGeneric
01/2021 - 11/2012
3Biomarkers (Surrogate Marker)IBA
01/2020 - 03/2014
3Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2020 - 09/2011
3Acetyl Coenzyme A (Acetyl-CoA)IBA
11/2017 - 11/2012
3Glutamine (L-Glutamine)FDA Link
11/2017 - 06/2012
3Proteins (Proteins, Gene)FDA Link
09/2011 - 08/2008
2CarbonIBA
01/2020 - 11/2017
2Temozolomide (Temodar)FDA LinkGeneric
12/2019 - 11/2016
2Acetates (Acetic Acid Esters)FDA Link
11/2017 - 12/2014
2Deoxyglucose (2 Deoxy D glucose)IBA
11/2012 - 11/2009
2NF-kappa B (NF-kB)IBA
04/2009 - 08/2008
1LipidsIBA
10/2021
1Pyruvic Acid (Pyruvate)IBA
01/2021
1Amino AcidsFDA Link
01/2020
1GadoliniumIBA
01/2020
1Glycine Dehydrogenase (Decarboxylating)IBA
01/2020
1EnzymesIBA
01/2020
1NucleotidesIBA
01/2020
1Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)IBA
01/2020
1Histones (Histone)IBA
01/2018
1Glutamic Acid (Glutamate)FDA Link
11/2017
1Carmustine (FIVB)FDA Link
11/2016
1Protons (Proton)IBA
11/2016
1APTIBA
03/2014
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
04/2013
1Phosphates (Orthophosphate)IBA
04/2013
1Fibroblast Growth Factor-23IBA
04/2013
1Oxygen (Dioxygen)IBA
11/2012
1isocitric acid (isocitrate)IBA
01/2012
1Oxidoreductases (Dehydrogenase)IBA
01/2012
1Nucleic AcidsIBA
09/2011
1imetelstatIBA
01/2010
1Telomerase (Telomerase Reverse Transcriptase)IBA
01/2010
1Coloring Agents (Dyes)IBA
11/2009
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
05/2009
1TOR Serine-Threonine KinasesIBA
05/2009

Therapy/Procedure

4Radiotherapy
01/2021 - 01/2016
2Therapeutics
11/2021 - 11/2016
2Drug Therapy (Chemotherapy)
01/2021 - 03/2014
1Neck Dissection (Radical Neck Dissection)
03/2020
1Operative Surgical Procedures
11/2016
1Craniotomy
02/2012